The FXI deficiency database (version 2.2) is being migrated to a new format with the same URL and we hope this upgraded website will be ready in 2016. On the changeover, this old website will be renamed www.factorxi2009.org.
The FXI deficiency database has recently been updated (September 2009) to include several new mutations and publications
Please take a look at our recent publication:
Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency.
Saunders RE, Shiltagh N, Gomez K, Mellars G, Cooper C, Perry DJ, Tuddenham EG, Perkins SJ. Thromb Haemost. 2009 102(2):287-301.
The information contained on this web site is provided for scientific research purposes only. We do not give medical advice or recommend any particular treatment for specific individuals. Click here for patient information.
There are currently 192 disease causing mutations in the FXI gene compiled within this database corresponding to 487 FXI deficient patients reported in literature. Mutations are characterized with a Type I or Type II phenotype.
We would like to thank the Welcome Trust and MRC for financial support.
The following people worked on this project:
The information contained on this web site is provided for research purposes only. All information and content on this web site are protected by copyright. All rights are reserved.