In Depth Variant Analysis:  Unspecified (V403M) (p.Val403Met)
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Unspecified (V403M)
p.Val403Met (Legacy AA No. 385)
Variant Type:  
Point
Domain:  
Serine Protease
Codon Change: 
Variant Effect: 
Missense
No. of Patients Reported: 
0
Phenotype: 
U
Allele Count *: 
-
Allele Number *: 
-
Allele Frequency *: 
-
Variant Comments & Reference:
Heterodimer trapping. Duga & Salomon 2013Residue Information:
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Substitution Analysis:
Structural Implications:
Val403 is a buried residue  (surface accessibility value = 0 ).
Val403 is in a region of secondary structure within the FXI domains.
The DSSP assignment for this residue is ... E.
Val403 is in a region of secondary structure within the FXI domains.
The DSSP assignment for this residue is ... E.
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