Variant Comments & Reference:

Lys101 is a highly conserved residue positioned near Cys103, which is involved in a disulphide linkage. Although this substitution involves amino acids with similar physical and chemical properties, the change may affect local conformation. Hill et al 2005

Patient Information: Show

Patient_ID	Age	Gender	Race	FXI:C%	FXI:Ag(%)	Inheritance	Other Variants	Severity	Comments	Reference
168	38	M		38		Heterozygote		Mild	Asymptomatic	Hill et al 2005

Structural Interpretation:

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